Clients

A selection of our clients ranging from midsize to large Corporations

Applichem (GER) Beiersdorf AG (GER) Biosyntech AG (CH) ChemCon GmbH (GER) Covance Labs (USA) Dr. Eckert GmbH (GER) Genibio (FRA) GlaxoSmithKline (USA) Hanalab (Korea) Hort Research (NZ) ICN Pharmaceuticals, INC (USA)

Inalco Pharmaceuticals (USA) Juvantia Pharma (FIN) Lilly Forschung GmbH (GER) MRC Medical Research Council (UK) New England Medical Center (USA) Procter & Gamble (USA) SAL DRU SYN Laboratories Ltd (INDIA) SchwarzBioscience GmbH (GER) Sennchem (CH) Sussex Research Laboratories Inc (CAN)

and several academic facilities

The Adelaide University (AU) Universität Bonn (GER) Universität Erlangen (GER) Uniklinik Regensburg (GER)

Uniklinik Wien (AUT) University of Oxford (UK) University of Illinois, Chicago (USA)

Publications

A list of selected publications of Dr. Wieczorek, Dr. Thimm and Prof. Thiem can be found below.

Dr. Eusebius Wieczorek
	Unusual Reactions of Enopyranuronates with Hydroxy Acid Esters under Ferrier Conditions. E. Wieczorek, J. Thiem Synlett 1997, 467 - 468
	Preparation of modified glycosyl glycerol derivatives by glycal rearrangement. E. Wieczorek, J. Thiem Carb. Res. 307, 263 - 270 (1998)
	Synthesis of Glycoside Derivatives Employing the Ferrier Rearrangement. E. Wieczorek, J. Thiem J. Carbohydr. Chem. 17, 785 - 809 (1998)
	Synthesis of Modified Oligosaccharide Derivatives by Ferrier Rearrangement. E. Wieczorek, J. Thiem Polish J. Chem. 73, 1111 - 1121 (1999)
	Glycals - Extensive interesting and inexpensive starting materials for building blocks synthesis. E. Wieczorek Acros Organics Acta 10, 13-14 (2003)
Dr. Julian Thimm
	Preparative enzymatic synthesis of Uridine-5’-diphospho-N-acetylglucosamine. J. Thimm, U. Korf, J. Thiem Synlett 1991, 317
	Synthesis of functionalized thiodisaccharides by conjugate addition. B. Becker, J. Thimm, J. Thiem J. Carbohydr. Chem., 15 (9) 1179-1181 (1996)
	Celery (Apium graveolens L.) parenchyma cell walls examined by atomic force microscopy: effect of dehydration on cellulose microfibrils. J. C. Thimm, D. J. Burritt, W. A. Ducker, L. D. Melton Planta 212(1) 25-32 (2000)
	Influence on the reversibility of hydroquinone/p-benzoquinone systems of potential-induced surface roughening of a polycrystalline gold electrode. A. Babaei, A.J. McQuillan, J. Thimm, and L.F. Sharabiani Bull. Electrochem. 18(11): 521-524 (2002)
	Celery (Apium graveolens) parenchyma cell walls: cell walls with minimal xyloglucan. J.C. Thimm, I.M. Sims, R.H. Newman, D.J. Burritt, W.A. Ducker, L.D. Melton Plant. Physiol. 116(2): 164-171 (2002)
	Imaging real-time aggregation of Amyloid Beta Protein (1-42) by atomic force microscopy: role of imaging medium, solvents, agonists and antagonists. A. Parbhu, H. Lin, J. Thimm, R. Lal J. Peptides 23(7): 1265-1270 (2002)
	Microtubule-dependent Oligomerization of Tau: Implications for Physiological Tau Function and for Tauopathies. V. Makrides, T.E. Shen, J. Thimm, B.L. Smith, R. Bhatia, R. Lal, and S.C. Feinstein Cover in J. Biol. Chem. 237(35): 33298-33304 (2003)
	Calcium-dependent Open/Closed Conformations and Interfacial Energy Maps of Reconstituted Hemichannels. Julian Thimm, Adam Mechler, Hai Lin, Seung Rhee, and Ratnesh Lal J. Biol. Chem. 280(11): p. 10646-10654 (2005)
	Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains. K. Dierck, K. Machida, A. Voigt, J. Thimm, M. Horstmann, W. Fiedler, B.J. Mayer and P. Nollau Nature Methods 3(9), 737-744 (2006)
	Convenient random glycosylation of unprotected non-reducing disaccharides. Andreas Steinmann, Julian Thimm, Joachim Thiem Eur. J. Org. Chem. 2007 DOI 10.1002/ejoc.200700504
Prof. Joachim Thiem (Hamburg University)
	Syntheses of Sugar Derived Heterotricyclic Lactams. C.E. Sowa, J. Kopf, J. Thiem J. Chem. Soc., Chem. Commun. 1995, 211-212
	Multi-enzyme system for a one-pot synthesis of sialyl T-antigen. V. Kren, J. Thiem Angew. Chem. 107, 979-981 (1995); Angew. Chem. Int. Ed. Engl. 34, 893-895(1995)
	Glycosylation Employing Bio-Systems - From Enzymes to Whole Cells. V. Kren, J. Thiem Chem. Soc. Rev., 26, 463-474 (1997)
	Von D-Glucose zu einem neuen chiralen Cyclooctenon. B. Werschkun, J. Thiem Angew. Chem., 109, 2905-2906 (1997); Angew. Chem. Int. Ed. Engl., 36, 2793-2794 (1997)
	Synthesis of a Fucose Hexasaccharide. M. Ludewig, J. Thiem Synthesis 1998, 56-62
	Synthesis of novel starch-derived AB-type polyurethanes. F. Bachmann, J. Reimer, M. Ruppenstein, J. Thiem Macromol. Rapid Commun. 19, 21-26 (1998)
	Synthesis of symmetric difucopyranose dianhydrides. M. Ludewig, D. Lazarevic, J. Kopf, J. Thiem J. Chem. Soc., Perkin Trans 1, 1998, 1751-1752
	Regio- and stereoselective introduction of ether-linked carboxylic side chains into carbohydrates by conjugate addition reactions B. Becker, J. Thiem Carbohydr. Res., 308, 77-84 (1998)
	Regioselective Fucosylation using L-Galactosyltransferase from Helix pomatia. Bornaghi, L. Keating, H. Binch, H. Bretting, J. Thiem Eur. J. Org. Chem., 1998, 2493-2497
	Synthesis of a N-Glucoasparagine Analogon as a Building Block for a V3-Loop Glycopeptide from GP120 of HIV-I. A. Schäfer, G. Klich, M. Schreiber, H. Paulsen, J. Thiem Carbohydr. Res., 313, 107-116 (1998)
	Sigmatropic Rearrangement of Uronic Acid Derived Saccharide Allyl Ketene Acetals. A Study of Stereochemistry and Structural Limitations. B. Werschkun, J. Thiem Synthesis, 1999, 121-137
	Chemoenzymatic synthesis of spacer-linked oligosaccharides for the preparation of neoglycoproteins R. Gonzalez Lio, J. Thiem Carbohydr. Res., 317, 180-190 (1999)
	Synthesis of Novel Donor Mimetics of UDP-Gal, UDP-GlcNAc and UDP-GalNAc as Potential. Transferase Inhibitors A. Schäfer, J. Thiem J. Org. Chem. 65, 24-29 (2000)
	Enzymatic Synthesis of Galß1-3GlcNAc Derivatives Utilizing a Phosphorylase from Bifidobacterium bifidum 20082. E. Farkas, J. Thiem, F. Krzewinski, S. Bouquelet Synlett 2000, 728-730
	Sialidase-catalyzed transsialylation using polymer-supported solution-phase techniques D. Schmidt, J. Thiem Chem. Comm. 2000, 1919-1920
	Chemoenzymatic synthesis of sialyl oligosaccharides with sialidases employing transglycosylation methodology. D. Schmidt, B. Sauerbrei, J. Thiem J. Org. Chem 65, 8518-8526 (2000)
	Stereoselektive photochemical transformations of hexopyranosyl imides to highly functionalised heterocycles. S. Thiering, C.E. Sowa, J. Thiem J. Chem. Soc., Perkin Trans. 1, 801 - 806 (2001)
	Synthesis of Aminosaccharide-derived Polymers with Urea, Urethane and Amide Lieskopes. F. Bachmann, M. Ruppenstein, J. Thiem J. Polym. Science A, Polym. Chem. 39, 2332 - 2341 (2001)